For Research Purposes Only · Not for Human Consumption · Not FDA Approved
TSM10

Buy Tesamorelin 10mg

Product SKU: TSM10

$ 90 per vial

  • Synthetic 44-amino-acid peptide analog of Growth Hormone-Releasing Hormone (GHRH).
  • eatures a trans-3-hexenoic acid moiety attached to the N-terminal Tyr¹, which significantly enhances resistance to enzymatic degradation by Dipeptidyl Peptidase-4 (DPP-4) compared to native GHRH.
  • Acts as a selective GHRH receptor agonist on pituitary somatotrophs, activating intracellular cAMP/PKA signaling cascades to trigger endogenous growth hormone (GH) synthesis and secretion.
Description

About

Buy Tesamorelin 10mg

Tesamorelin 10mg For Sale

Tesamorelin 10mg is a research-grade peptide supplied as a lyophilized powder for laboratory studies. It is a synthetic analog of growth hormone-releasing hormone (GHRH) and interacts with GHRH receptors involved in growth hormone signaling.

Researchers can buy Tesamorelin 10mg at Neuro Peptides for research purposes. Tesamorelin is commonly studied in areas such as endocrinology, peptide pharmacology, metabolism, and molecular biology.

Tesamorelin 10mg can be used in research involving GHRH receptor activation, growth hormone secretion, insulin-like growth factor-1 (IGF-1) signaling, and metabolic pathways. Each vial is intended strictly for laboratory research and is not for human or veterinary use.

Tesamorelin Specifications

Specification Details
Full Name Tesamorelin Acetate
Peptide Sequence (trans-3-hexenoyl)-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂
CAS Number 218949-48-5
PubChem CID 16137828
Molecular Weight 5135.9 g/mol
Molecular Formula C₂₂₁H₃₆₆N₇₂O₆₇S
Appearance White to off-white lyophilized powder

Tesamorelin Structure

Tesamorelin is a synthetic 44-amino-acid analogue of human growth hormone-releasing hormone (GHRH). Its structure includes an N-terminal trans-3-hexenoyl modification designed to improve stability relative to endogenous GHRH. The peptide retains activity at the GHRH receptor and stimulates downstream growth hormone signaling.

Tesamorelin: Mechanism of Action

Tesamorelin is still being studied by researchers in relation to how it interacts with growth hormone-releasing hormone receptors and signaling mechanisms within endocrine and metabolic pathways. According to experimental studies, Tesamorelin acts as a selective GHRH receptor agonist, which makes it useful for understanding the physiology of growth hormone and the associated signaling pathways.

1. Growth Hormone-Releasing Hormone (GHRH) Receptor Activation

Extensive research has been conducted to study the binding properties of tesamorelin, which selectively binds to GHRH receptors present on the anterior pituitary somatotroph cells. In vitro experiments involve examining the mechanism by which receptor activation leads to intracellular signal transduction for the physiological secretion of growth hormone.

2. Growth Hormone and IGF-1 Signaling

Experimental studies indicate that Tesamorelin is extensively used to study the link between growth hormone release and IGF-1 signaling. Researchers still try to understand the mechanisms through which these related processes control cellular proliferation, protein metabolism, tissue physiology, and endocrine regulation within the laboratory setting.

3. Metabolic and Cellular Research

Present studies employ Tesamorelin for examining the regulation of metabolism through peptides, cell signaling, and cellular communication. Investigations are being conducted to understand its effects on the molecular mechanisms related to lipid metabolism, energy balance, and endocrinology.

Tesamorelin : Research Applications

Tesamorelin 10mg is used for numerous scientific studies in such fields as:

Endocrinology: growth hormone research, GHRH receptor signaling, and endocrine regulation.

Molecular biology: intracellular signaling pathway research and cell communication by peptides.

Metabolic studies: metabolism of lipids, energy balance, and metabolic homeostasis.

Cell biology: cell response to hormones and biological actions via receptors.

Pharmacology of GHRH analogs: GHRH receptor specificity and peptide receptor interactions.

Biochemistry: protein signaling, endocrine signaling pathways, and peptide mechanism of action.

Storage Instructions

The storage process is critical for maintaining the purity, stability, and biological activity of Tesamorelin 10mg in all research experiments.

1. Storage Recommendations of Lyophilized Powder:

Unopened bottles of Tesamorelin (or any other peptides) generally should be stored at temperatures lower than -20°C. In case the bottle remains closed, it can also be stored at 2–8°C for 12 months. The lyophilized powder needs to be protected from direct sunlight, high humidity levels, and frequent changes of temperature.

2. Storage Recommendations of Reconstituted Solution:

Upon reconstitution, the reconstituted solution should be stored in a lab refrigerator at 2–8°C. Researchers are required to use aseptic technique while preparing the solution.

FAQs

Q1. What is Tesamorelin 10mg used for?

Tesamorelin 10mg is popularly used in laboratory studies to study the effects of growth hormone-releasing hormone (GHRH) receptor activation, growth hormone release, IGF-1 action, physiology of the endocrine system, and metabolic actions of peptides.

Q2. Which type of peptide is Tesamorelin?

Tesamorelin is an analog of the growth hormone-releasing hormone (GHRH). The particular peptide is made synthetically for the purpose of activating the receptors of GHRH and is frequently used for the study of the physiology of the endocrine system.

Q3. How should Tesamorelin 10mg be stored?

Store unopened lyophilized vials at -20°C or below for long-term storage. If unopened, the peptide may also be refrigerated at 2–8°C for up to 12 months. After reconstitution, store the solution at 2–8°C and avoid repeated freeze-thaw cycles.

Q5. In which areas of study is Tesamorelin usually utilized?

The primary areas of study in which Tesamorelin is used are: endocrinology, pharmacology of peptides, molecular biology, metabolic studies, cell biology, and growth hormone signaling pathway studies.

Q6. Is Tesamorelin 10mg third-party tested?

Yes. Neuro Peptides provides third-party tested Tesamorelin 10mg to ensure product purity, identity, and quality. Researchers can review the available batch-specific testing documentation to verify the product’s analytical results.

Q7. Is a Certificate of Analysis (COA) available for Tesamorelin 10mg?

Yes. Neuro Peptides provides a Certificate of Analysis (COA) for Tesamorelin 10mg. Researchers can review the COA to verify the peptide’s identity, purity, and batch-specific testing results before purchasing.

Q8. What is the purity of Tesamorelin 10mg?

The purity of Tesamorelin 10mg should be determined through analytical testing, such as high-performance liquid chromatography (HPLC). Researchers should refer to the batch-specific Certificate of Analysis to verify the reported purity percentage and other relevant analytical results.

Q9. What is the difference between Tesamorelin and Sermorelin?

Both Tesamorelin and Sermorelin are synthetic analogs of growth hormone-releasing hormone (GHRH), but they differ in their molecular structures.

Tesamorelin is a modified analog of full-length human GHRH, whereas Sermorelin contains the first 29 amino acids of human GHRH. Both peptides are investigated for their interactions with GHRH receptors and their effects on growth hormone signaling.

Q10. What form does Tesamorelin 10mg come in?

Neuro Peptides supplies Tesamorelin 10mg as a lyophilized powder in a sealed laboratory vial. Lyophilization removes water from the formulation under controlled conditions, producing a dry preparation suitable for storage under the manufacturer’s specified conditions.

Final Thoughts

Tesamorelin 10mg is a research-grade peptide used in laboratory studies involving GHRH receptor activity, growth hormone signaling, IGF-1 pathways, and metabolic processes. Its specific activity at GHRH receptors makes it useful for research in endocrinology, peptide pharmacology, and molecular biology.

Each vial is produced under strict quality control standards and is intended for laboratory research only. Not for human or veterinary use.

Research Disclaimer

Regulatory Status: Tesamorelin is the active ingredient in FDA-approved prescription products for a specific medical indication. Neuro Peptides Tesamorelin 10mg is sold solely as a research material and is not an FDA-approved pharmaceutical product or intended for human use.

References

  1. Falutz, J., Allas, S., Blot, K., Potvin, D., Kotler, D., Somero, M., … & Grinspoon, S. (2007). Metabolic effects of a growth hormone–releasing factor in patients with HIV. New England Journal of Medicine, 357(23), 2359-2370. 
  2. Stanley, T. L., Feldpausch, M. N., Oh, J., Branch, K. L., Lee, H., Torriani, M., & Grinspoon, S. K. (2014). Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial. Jama, 312(4), 380-389. 
  3. National Center for Biotechnology Information (NCBI). PubChem Compound Summary for Tesamorelin.
Certificate of Analysis

COA · Buy Tesamorelin 10mg

Every batch of Buy Tesamorelin 10mg is independently tested by an accredited third-party laboratory. The certificate below is the lot record for Buy Tesamorelin 10mg 10 mg.

Certificate of Analysis

NRP#00013
Client:
Neuro Peptides
Sample:
Tesamorelin 10mg
Batch:
202603TSM10
Tests Requested:
Standard + Endotoxins + Sterility
Appearance:
White Lyophilized Powder in 3mL Vial
Analysis Conducted on:
03/28/2026
Report Issued on:
08/20/2026
TestMethodResultSpecification
IdentityHPLC-DADTesamorelinTesamorelinPass
PurityHPLC-DAD99.89>99% by HPLCPass
QuantityHPLC Analyte Concentration Curve Assay10.9810mgPass
EndotoxinsLAL ELISA0.145 EU/mL≤ 0.5 EU/mLPass
SterilityPour PlateNo GrowthNo GrowthPass
Disclaimer: The data contained in this report is representative of the received sample. This analysis is for informational purposes only. The tested substances are intended for research use only and are not approved for human or veterinary use, diagnostic, therapeutic, or clinical applications. All data was obtained under standard laboratory conditions.
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Full lot-specific COA documentation is available on request from our research support team.

Storage guidelines

Handling & storage

  1. 01

    Before Reconstitution (Powder Form)

    Store at controlled room temperature Keep in original sealed container Do not freeze the vials Maintain stable temperature conditions

  2. 02

    After Reconstitution (Liquid Form)

    Refrigerate immediately at 36°F to 46°F Store at 2°C to 8°C consistently Keep refrigerated between uses Place in clean refrigerator compartment

  3. 03

    Important Storage Precautions

    If left out for more than 4 hours, contact supervisor Do not use if the temperature exposure is exceeded Return to refrigerator promptly after use Monitor storage conditions regularly

Chemical properties

Structure & specification

Structure & specification
Molecular Formula
C221H366N72O67S
Molecular Mass
5136 g/mol
Monoisotopic Mass
5134.7233503 Da
Polar Area
Extremely high
Complexity
Extremely high
XLogP
-23.3
Heavy Atom Count
Very high
Hydrogen Bond Donor Count
High
Hydrogen Bond Acceptor Count
High
Rotatable Bond Count
187