For Research Purposes Only · Not for Human Consumption · Not FDA Approved
buy Semaglutide 20mg

Buy Semaglutide 20mg

Product SKU: SM

$ 99 per vial · 20mg

  • Semaglutide 10mg prepared for laboratory-based peptide research
  • Designed for controlled analytical and in-vitro investigations
  • Third-party tested for research quality and consistency
  • Convenient 10mg vial for scientific research applications
For research use only · Not for human consumption · Not FDA approved
SKU SM Categories ,

20 in stock

Description

Semaglutide 20mg For Sale

Semaglutide 20mg is available for laboratory and scientific research involving GLP-1 receptor signaling, metabolic pathways, endocrine regulation, and glucose-related mechanisms.

Semaglutide is a synthetic glucagon-like peptide-1 (GLP-1) analogue and GLP-1 receptor agonist. It shares approximately 94% sequence homology with native human GLP-1 and was developed with structural modifications that increase its stability and extend its biological activity compared with naturally occurring GLP-1.

A key feature of semaglutide is its resistance to degradation by dipeptidyl peptidase-4 (DPP-4). Its molecular structure also promotes albumin binding, which helps reduce renal clearance and protects the peptide from rapid metabolic degradation. These properties have made semaglutide an important compound for studying prolonged GLP-1 receptor activation and related metabolic signaling pathways.

Research involving semaglutide has examined several interconnected biological processes, including glucose-dependent insulin signaling, glucagon regulation, gastrointestinal signaling, gastric emptying, and metabolic homeostasis. Because GLP-1 receptors are expressed in multiple tissues, semaglutide has also been studied in relation to communication between the pancreas, gastrointestinal tract, liver, and central nervous system.

Semaglutide has a molecular formula of C187H291N45O59 and a molecular weight of approximately 4,113.58 g/mol. Its structural modifications include an amino-acid substitution that improves resistance to DPP-4 degradation and a fatty di-acid side chain that contributes to albumin binding.

Semaglutide 20mg supplied by Neuro Peptides is intended strictly for laboratory research. This research product is not FDA-approved and is not intended for human or veterinary use, diagnosis, treatment, or consumption.

Semaglutide Molecular Structure

Semaglutide is a synthetic peptide structurally related to naturally occurring glucagon-like peptide-1 (GLP-1). Its molecular modifications improve stability, increase resistance to enzymatic degradation, and prolong biological activity.

Property Details
Peptide Type GLP-1 receptor agonist
Amino Acid Length 31 amino acids
Molecular Formula C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight Approximately 4,113.6 Da
Form Lyophilized powder
Structural Relationship Modified analogue of human GLP-1
Research Areas GLP-1 receptor signaling, metabolic regulation, endocrine pathways, and related biological mechanisms

The molecular design of Semaglutide has made it a widely studied peptide in laboratory research involving GLP-1 receptor signaling and metabolic pathways.

How Does Semaglutide Work in A Research Setting?

Semaglutide is a Glucagon-like-peptide-1 (GLP-1) receptor agonist. GLP-1 agonists (also known as GLP-1 receptor agonists, GLP-1 analogs or incretin mimetics) are a group of compounds used in the treatment of T2DM.

Semaglutide is being investigated through several key mechanisms:

1. Appetite Regulation

GLP-1 is a natural incretin hormone produced by L-cells in the intestines. This hormone plays a key part in the overall process that regulates food intake and appetite. Semaglutide may have the ability to mimic the incretin hormone GLP-1. 

Semaglutide research has shown the ability to mimic and activate GLP-1 receptors in the brain involved in hunger and satiety. This may result in reduced feelings of hunger and, as a result, reduced calorie intake.

2. Delayed Gastric Emptying

Delayed gastric emptying is a process whereby the rate at which food leaves the stomach and enters the small intestine is slowed down. Research shows that Semaglutide is able to induce this process. As a result, delayed gastric emptying can lead to a prolonged sense of fullness and satiety, further reducing food intake.

3. Glucose-dependent Insulin Secretion

Semaglutide can increase insulin secretion in a glucose-dependent manner. This means that insulin secretion is increased when blood glucose levels are high. This leads to a reduced risk of hypoglycemia and better control of blood sugar levels.

4. Glucagon Suppression

The pancreas produces the hormone called glucagon, essential in regulating blood sugar levels. The liver is stimulated to release glucose into the bloodstream. This is where Semaglutide comes in. Semaglutide works by binding to GLP-1 receptors in the pancreas. This may lead to the suppression of the release of glucagon. This allows Semaglutide to lower the blood sugar levels in subjects with diabetes. By reducing glucagon levels, semaglutide further helps to maintain healthy blood sugar levels, which is particularly beneficial for individuals with type 2 diabetes.

5. Energy Expenditure and Lipid Metabolism 

Studies suggest the possibility of increased energy expenditure and fat burning. This could result in decreases in body weight and improvements in body composition. It may also have a positive effect on lipid metabolism. This could initiate favourable changes in cholesterol and triglyceride levels.

These mechanisms all combine to make semaglutide a very effective weight loss medication when used as part of a comprehensive weight management program that includes a healthy diet and exercise. The sustained activation of the GLP-1 receptors by semaglutide is a key factor in its ability to achieve significant and sustained weight loss in individuals with overweight or obesity.

Frequently Asked Questions

1. What is Semaglutide 20mg used for in research?

Semaglutide 20mg is studied in laboratory research involving GLP-1 receptor signaling, glucose-related pathways, endocrine regulation, metabolic signaling, and energy homeostasis.

2. Is Semaglutide a GLP-1 peptide?

Yes. Semaglutide is a synthetic GLP-1 analogue and GLP-1 receptor agonist. It was designed to have greater stability and a longer duration of activity than naturally occurring GLP-1.

3. Is Semaglutide 20mg FDA-approved?

This Semaglutide 20mg research product is not FDA-approved. It is supplied strictly for laboratory research and is not intended for human or veterinary use.

4. Is Semaglutide 20mg third-party tested?

Yes. Semaglutide 20mg is third-party tested to provide independent verification of relevant quality and purity specifications.

5.Does Semaglutide 20mg come with a COA?

Yes. A Certificate of Analysis (COA) is available for Semaglutide 20mg. The COA provides batch-specific testing information, including relevant purity and quality data.

6. How long does Semaglutide 20mg shipping take?

Orders typically arrive within 3 to 5 business days, depending on the destination, carrier service, and shipping conditions.

7. Is research-grade Semaglutide the same as prescription Semaglutide?

No. Research-grade Semaglutide is supplied specifically for laboratory investigation. It is not a prescription medication, compounded drug, or substitute for an approved pharmaceutical product.

8. How should Semaglutide 20mg be handled for research?

Semaglutide should be handled according to appropriate laboratory protocols and the storage instructions provided with the research material. Researchers should also review the product documentation and COA before use.

9. What makes Semaglutide useful in metabolic research?

Semaglutide is widely studied because of its prolonged GLP-1 receptor activity and its relevance to signaling pathways involving glucose regulation, insulin response, gastrointestinal signaling, and metabolic homeostasis.

Final Thoughts

Semaglutide remains an important compound in modern metabolic research because of its prolonged GLP-1 receptor activity and its relevance to glucose signaling, endocrine regulation, gastrointestinal pathways, and metabolic homeostasis.

Semaglutide 20mg from Neuro Peptides is supplied for laboratory and scientific research, with third-party testing and a Certificate of Analysis (COA) available for quality verification.

This product is intended strictly for research purposes and is not intended for human or veterinary use, diagnosis, treatment, or consumption.

References

  1. Wilding, J. P., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., … & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002.
  2. Davies, M., Færch, L., Jeppesen, O. K., Pakseresht, A., Pedersen, S. D., Perreault, L., … & Lingvay, I. (2021). Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial. The Lancet, 397(10278), 971-984.

Certificate of Analysis

Lab verification

Storage guidelines

Handling & storage

  1. 01

    R⁠efrigera​tio‌n Guideline‌s‌

    Store unuse​d pens in the refrigerat​or at 36°F to 46°F Do no⁠t fr⁠ee⁠ze t‌he medicati​on After‍ f⁠irst use, Ozemp‍ic can be at 36°F–46°‌F (2°C–8°C) or‌ 59°F‍–86°F (15°C–‍30°C) for up to 56 d⁠a​ys. Oze⁠mpic pens can be​ used up⁠ t‍o 56 days a⁠fter first use; Wegovy si‍ngle-dose pens​ must be discarded af⁠ter use. Wegovy m‌ay stored 8°C–30°C (46‍°F–86°F)⁠ up to 28 days before use.

  2. 02

    General Stora​ge Tips

    Keep the pen cap on when storing Sto‌re a​way from dir‍ec⁠t light and heat Keep in its origina⁠l provided conta⁠iner. Room temp stora​ge duratio‍ns a‍re defin⁠ed by‍ product: 56 days fo​r‌ Oz‍empic, 28​ days for‍ Wego​vy (​single dose). Mu⁠st remove and discard‍ nee​dle​ after each⁠ injectio‍n; do n⁠ot st‍ore pen with needle att⁠ached.⁠ Visual​ inspec⁠ti‌on​ before‌ injection (​clear, colo‌rl‌ess) is critical.​ Once the first dose is taken, you should note the date to track its usable period (56 days for Ozempic; 28 days for Wegovy)

  3. 03

    Sa‌fety⁠ Prec‍autions

    Keep out‌ of reach of children⁠ Store in​ a high, secure location Always lock safety caps‌ on con⁠tainers Ensure med‍ication is not acc​ess⁠i‌ble t‍o pe‍ts Do not store pens with needles attached.

  4. 04

    Proper Di‌spos​al

    Ne⁠ver flush medicat‌ion do‌wn the⁠ toilet Use medicine take-back progra⁠ms for d‍is‍posal Visit the FDA website for safe disposal guideli​nes

Chemical properties

Structure & specification

Structure & specification
Dosage
5mg,10mg,15mg,20mg,30mg
Vial Size
3ML,10ML
Molecular Formula
C187H291N45O59
Molecular Mass
4114 g/mol
Monoisotopic Mass
4111.115377
Polar Area
2250
Complexity
12200
XLogP
-43.5
Heavy Atom Count
347
Hydrogen Bond Donor Count
72
Hydrogen Bond Acceptor Count
88
Rotatable Bond Count
180

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